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Olivopontocerebellar Atrophies: Disease Bioinformatics

Research of Olivopontocerebellar Atrophies has been linked to Atrophy, Ataxia, Multiple System Atrophy, Spinocerebellar Degeneration, Cerebellar Ataxia. The study of Olivopontocerebellar Atrophies has been mentioned in research publications which can be found using our bioinformatics tool below. Researched pathways related to Olivopontocerebellar Atrophies include Reflex, Pathogenesis, Localization, Transport, Aging. These pathways complement our catalog of research reagents for the study of Olivopontocerebellar Atrophies including antibodies and ELISA kits against LURCHER, CHAT, CSF2, FANCA, FXN.

Top Research Reagents

We have 2101 products for the study of Olivopontocerebellar Atrophies that can be applied to Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Western Blot from our catalog of antibodies and ELISA kits.

NBP3-25371
Immunohistochemistry-Paraffin: Ataxin-3 Antibody (HL1909) - Azide and BSA Free [NBP3-25371] - Ataxin 3 antibody [HL1909] detects Ataxin 3 protein at nucleus by immunohistochemical analysis. Sample: Paraffin-embedded rat brain. Ataxin 3 stained by Ataxin 3 antibody [HL1909] (NBP3-25371) diluted at 1:100. Antigen Retrieval: Citrate buffer, pH 6.0, 15 minWestern Blot: Ataxin-3 Antibody (HL1909) - Azide and BSA Free [NBP3-25371] - Non-transfected (-) and transfected (+) 293T whole cell extracts (30 ug) were separated by 10% SDS-PAGE, and the membrane was blotted with Ataxin 3 antibody [HL1909] (NBP3-25371) diluted at 1:500. The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody.

Rabbit Monoclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

NBP1-30052
Western Blot: Choline Acetyltransferase/ChAT Antibody [NBP1-30052] - The decrease in protein expressions of c-kit, Choline Acetyltransferase/ChAT, nNOS and Cx43 in the colon of elderly humans. Expressions of c-kit, ChAT, nNOS and Cx43 proteins in colonic muscle layers detached from youth and older adults were examined by western blotting (n=4 per group), and similar reduction was observed. Image collected and cropped by CiteAb from the following publication (//pubmed.ncbi.nlm.nih.gov/30530917/) licensed under a CC-BY license.Immunocytochemistry/Immunofluorescence: Choline Acetyltransferase/ChAT Antibody [NBP1-30052] - Representative images of lumbar spinal cord sections at 130 days immunostained with Choline Acetyltransferase/ChAT. Scale bar, 200 um. Image collected and cropped by CiteAb from the following publication (https://embomolmed.embopress.org/lookup/doi/10.15252/emmm.201808888), licensed under a CC-BY license.

Goat Polyclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

24 Publications
NBP1-51689
Western Blot: Ataxin 1 Antibody (2F5) [NBP1-51689] - Analysis using ATXN1 mab against HEK293 (1) and ATXN1 higGFC transfected HEK293 (2) cell lysate. Immunocytochemistry/Immunofluorescence: Ataxin 1 Antibody (2F5) [NBP1-51689] - Immunofluorescence analysis of NTERA-2 cells using ATXN1 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.

Mouse Monoclonal
Species Human
Applications WB, ELISA, Flow

NBP1-52176
Immunocytochemistry/Immunofluorescence: Ly-6E Antibody [NBP1-52176] - Immunofluorescence analysis of paraformaldehyde fixed L929 cells (Mouse fibroblast cell line), permeabilized with 0.15% Triton. Primary incubation 1hr (10 ug/mL) followed by Alexa Fluor 488 secondary antibody (2 ug/mL), showing membrane staining. The nuclear stain is DAPI (blue). Negative control: Unimmunized goat IgG (10 ug/mL) followed by Alexa Fluor 488 secondary antibody (2 ug/mL).Flow Cytometry: Ly-6E Antibody [NBP1-52176] - Flow cytometric analysis of paraformaldehyde fixed NIH3T3 cells (blue line), permeabilized with 0.5% Triton. Primary incubation 1hr (10 ug/mL) followed by Alexa Fluor 488 secondary antibody (1 ug/mL). IgG control: Unimmunized goat IgG (black line) followed by Alexa Fluor 488 secondary antibody.

Goat Polyclonal
Species Mouse
Applications Flow, ICC/IF, PEP-ELISA

2 Publications
NBP1-80670
Immunohistochemistry-Paraffin: Thyroid Peroxidase Antibody [NBP1-80670] - Staining in human thyroid gland and cerebral cortex tissues using anti-TPO antibody. Corresponding TPO RNA-seq data are presented for the same tissues.Immunohistochemistry-Paraffin: Thyroid Peroxidase Antibody [NBP1-80670] - Staining of human cerebral cortex shows low expression as expected.

Rabbit Polyclonal
Species Human
Applications WB, IHC, IHC-P

4 Publications
NBP1-90063
Immunohistochemistry-Paraffin: Ataxin-2 Antibody [NBP1-90063] - Analysis in human testis and skeletal muscle tissues. Corresponding Ataxin-2 RNA-seq data are presented for the same tissues.Immunohistochemistry-Paraffin: Ataxin-2 Antibody [NBP1-90063] - Staining of human cerebellum, cerebral cortex, skeletal muscle and testis using Anti-Ataxin-2 antibody NBP1-90063 (A) shows similar protein distribution across tissues to independent antibody NBP1-90062 (B).

Rabbit Polyclonal
Species Human, Mouse
Applications ICC/IF, IHC, IHC-P

6 Publications
NBP1-90906
Immunohistochemistry-Paraffin: UDP glucose dehydrogenase Antibody [NBP1-90906] - Staining of human cerebral cortex, liver, prostate and rectum using Anti-UDP glucose dehydrogenase antibody NBP1-90906 (A) shows similar protein distribution across tissues to independent antibody NBP1-90997 (B).Western Blot: UDP glucose dehydrogenase Antibody [NBP1-90906] - Analysis in human cell lines A-549 and HEK293 using anti-UGDH antibody. Corresponding UGDH RNA-seq data are presented for the same cell lines. Loading control: anti-HSP90B1.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

NBP2-01743
Western Blot: Frataxin Antibody (1C12) [NBP2-01743] - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY Frataxin (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-Frataxin.Immunocytochemistry/Immunofluorescence: Frataxin Antibody (1C12) [NBP2-01743] Staining of COS7 cells transiently transfected by pCMV6-ENTRY Frataxin.

Mouse Monoclonal
Species Human
Applications WB, Flow, ICC/IF

NBP2-02450
Western Blot: PSP94/MSMB Antibody (OTI6C7) [NBP2-02450] - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY Prostate Secretory Protein/PSP (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-Prostate Secretory Protein/PSP.Immunocytochemistry/Immunofluorescence: PSP94/MSMB Antibody (OTI6C7) [NBP2-02450] - Staining of COS7 cells transiently transfected by pCMV6-ENTRY Prostate Secretory Protein/PSP.

Mouse Monoclonal
Species Human
Applications WB, ICC/IF, IHC

NBP2-02615
Western Blot: Glucose 1-dehydrogenase Antibody (2A7) [NBP2-02615] - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY Glucose 1-dehydrogenase (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-Glucose 1-dehydrogenase.Immunocytochemistry/Immunofluorescence: Glucose 1-dehydrogenase Antibody (2A7) [NBP2-02615] - Staining of COS7 cells transiently transfected by pCMV6-ENTRY Glucose 1-dehydrogenase.

Mouse Monoclonal
Species Human, Monkey, Primate
Applications WB, Flow, ICC/IF

NBP2-15365
Immunohistochemistry-Frozen: alpha-Synuclein Antibody [NBP2-15365] - Frozen-sectioned adult mouse hippocampus. Green: alpha Synuclein protein stained by alpha Synuclein antibody diluted at 1:250. Red: NeuN, stained by NeuN antibody [2Q158] diluted at 1:500.Western Blot: alpha-Synuclein Antibody [NBP2-15365] - Various tissue extracts (50 ug) were separated by 15% SDS-PAGE, and the membranes were blotted with alpha Synuclein antibody diluted at 1:2000 and competitor's antibody  diluted at 1:2000. The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

     1 Review

12 Publications
NBP2-16679
Western Blot: Glutamate Dehydrogenase Antibody [NBP2-16679] - Metabolic alterations in the MPC1-/- cells expressed significantly higher levels glutaminolysis related proteins GDH (Glutamate Dehydrogenase) and GLS (NBP2-29940), but there was no significant change in the PDHE1 protein expression in these cells as shown in representative western blots. The alpha-Tublin was used as loading control. ***P<0.001. Data were expressed as mean +/- SEM. Three replicated experiments were carried out with the similar results. Image collected and cropped by CiteAb from the following publication (www.oncotarget.com/lookup/doi/10.18632/oncotarget.18199) licensed under a CC-BY license.Immunocytochemistry/Immunofluorescence: Glutamate Dehydrogenase Antibody [NBP2-16679] - HeLa cells were fixed in ice-cold MeOH for 5 min. Green: Glutamate Dehydrogenase protein stained by Glutamate Dehydrogenase antibody  diluted at 1:500. Blue: Hoechst 33342 staining.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ELISA, ICC/IF

4 Publications
NBP2-25162
Western Blot: Tau Antibody (2E9) [NBP2-25162] - Analysis of different tissue lysates using mouse mAb to MAP-tau, NBP2-25162, dilution 1:2,000 in green: [1] protein standard (red), [2] rat brain, [3] rat spinal cord, [4] mouse brain, [5] mouse spinal cord. Tau protein is expressed as up to 9 different isoforms of different molecular weight, and so appears as multiple closely spaced bands in the range from 48 kDa to 67 kDa in the CNS and including larger big tau forms in the PNS, visible in lane 5.Immunocytochemistry/Immunofluorescence: Tau Antibody (2E9) [NBP2-25162] - Analysis of cortical neuron-glial culture from E20 rat stained with mouse mAb to MAP-tau, NBP2-25162, dilution 1:1,000 in green, and costained with chicken pAb to MAP2, dilution 1:5,000 in red. The blue is DAPI staining of nuclear DNA. NBP2-25162 antibody stains perikarya, dendrites and axons of neurons, while MAP2 antibody labels only dendrites and perikarya. As a result, perikarya and dendrites appear orange-yellow, since they contain both proteins.

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

5 Publications
NBP2-30377
Western Blot: TSEN54 Antibody [NBP2-30377] - Lane 1: Marker  [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10.  Lane 2: Human cell line RT-4.  Lane 3: Human cell line U-251MG sp.  Lane 4: Human plasma (IgG/HSA depleted).  Lane 5: Human liver tissue.  Lane 6: Human tonsil tissueImmunohistochemistry: TSEN54 Antibody [NBP2-30377] - Staining of human kidney shows moderate positivity in renal tubules.

Rabbit Polyclonal
Species Human
Applications WB, IHC, IHC-P

NBP2-31923
Immunocytochemistry/Immunofluorescence: ArgRS Antibody [NBP2-31923] - Immunofluorescent staining of human cell line U-2 OS shows localization to nuclear bodies & cytosol.Immunohistochemistry: ArgRS Antibody [NBP2-31923] - Staining of human testis shows distinct cytoplasmic positivity in a subset of cells in seminiferus ducts.

Rabbit Polyclonal
Species Human
Applications ICC/IF, IHC, IHC-P

NBP2-35208
SDS-Page: Recombinant Human Persephin Protein [NBP2-35208]


Species Human
Applications PAGE, BA

NB100-2564
Western Blot: FACA/FANCA Antibody [NB100-2564] - Detection of FANC A in transfected COS1 cell lysate.

Rabbit Polyclonal
Species Human
Applications WB

1 Publication
7954-GM/CF
Measured in a cell proliferation assay using TF-1 human erythroleukemic cells. The ED<sub>50</sub> for this effect is 6-30 pg/mL.


Species Human
Applications BA

3 Publications
NBP2-42388
Immunohistochemistry-Paraffin: LAMC2 Antibody (CL2980) [NBP2-42388] - Staining in human fallopian tube and liver tissues. Corresponding LAMC2 RNA-seq data are presented for the same tissues.Western Blot: LAMC2 Antibody (CL2980) [NBP2-42388] - Analysis in A-431 cells transfected with control siRNA, target specific siRNA probe #1 and #2, using Anti-LAMC2 antibody. Remaining relative intensity is presented. Loading control: Anti-GAPDH.

Mouse Monoclonal
Species Human
Applications WB, ICC/IF, IHC

4 Publications

Related Genes

Olivopontocerebellar Atrophies has been researched against:

Related PTMs

Olivopontocerebellar Atrophies has been studied in relation to posttranslational modifications (PTMs) including:

Alternate Names

Olivopontocerebellar Atrophies is also known as Atrophy, Olivopontocerebellar, Degeneration, Olivo-ponto-cerebellar, Degeneration, Olivopontocerebellar, Degenerations, Olivopontocerebellar, Olivo-ponto-cerebellar Atrophy.