Colorectal cancer, commonly referred to as colon cancer, originates in the colon (large intestine) or rectum, typically as adenomatous polyps. It is unknown what causes cancer yet familial adenomatous polposis (FAP) and hereditary nonpolyposis colorectal cancer (HNPCC) are thought to increase risk of developing colon cancer. HNPCC is also referred to as Lynch Syndrome which can be divided into type I and type II. Individuals with this specific diagnosis are commonly diagnosed at a younger age than those without this condition. However, HNPCC as well as FAP can be screened in genetic testing. Additionally, increasing age, inflammatory intestinal conditions, nationality, low fiber and high fat diet, diabetes, smoking, alcohol, obesity, and a sedentary lifestyle can contribute to its onset. Treatments for colon cancer include surgery, chemotherapy, radiation therapy, and targeted drug therapy.
Top Research Reagents
We have 3075 products for the study of Hereditary Nonpolyposis Colorectal Cancer that can be applied to Chromatin Immunoprecipitation (ChIP), Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Western Blot from our catalog of antibodies and ELISA kits.
Hereditary Nonpolyposis Colorectal Cancer is also known as Hereditary Non-polyposis Colon Cancer, Hereditary Nonpolyposis Colon Cancer, Hnpcc, Lynch Cancer Family Syndrome I, Lynch Syndrome.