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Chediak-higashi Syndrome: Disease Bioinformatics

Research of Chediak-higashi Syndrome has been linked to Immunologic Deficiency Syndromes, Albinism, Infective Disorder, Granulomatous Disease, Chronic, Albinism, Oculocutaneous. The study of Chediak-higashi Syndrome has been mentioned in research publications which can be found using our bioinformatics tool below. Researched pathways related to Chediak-higashi Syndrome include Chemotaxis, Phagocytosis, Secretion, Pigmentation, Pathogenesis. These pathways complement our catalog of research reagents for the study of Chediak-higashi Syndrome including antibodies and ELISA kits against APOH, C4B, CAT, LYST, CTLA4.

Top Research Reagents

We have 3007 products for the study of Chediak-higashi Syndrome that can be applied to Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Western Blot from our catalog of antibodies and ELISA kits.

MAP4K6 Antibody
NBP1-22990
Western Blot: MAP4K6 Antibody [NBP1-22990] - Whole cell lysate from HeLa and mouse NIH3T3 cells at 0.04 mcg/ml (A) and 1 mcg/ml (B) and used for IP at 3 mcg/mg lysate.

Rabbit Polyclonal
Species Human, Mouse
Applications WB, IP

5 Publications
KCNE1 Antibody (5B12) - Azide and BSA Free
H00003753-M01
Western Blot: KCNE1 Antibody (5B12) [H00003753-M01] - Analysis of KCNE1 over-expressed 293 cell line, cotransfected with KCNE1 Validated Chimera RNAi ( Cat # H00003753-R01V ) (Lane 2) or non-transfected control (Lane 1). Blot probed with KCNE1 monoclonal antibody (M01), clone 5B12 (Cat # H00003753-M01 ). GAPDH ( 36.1 kDa ) used as specificity and loading control.Western Blot: KCNE1 Antibody (5B12) [H00003753-M01] - analysis of KCNE1 expression in transfected 293T cell line by KCNE1 monoclonal antibody (M01), clone 5B12. Lane 1: KCNE1 transfected lysate (14.7 KDa). Lane 2: Non-transfected lysate.

Mouse Monoclonal
Species Human, Rat, Canine
Applications WB, ELISA, ICC/IF

4 Publications
Rab27a Antibody (1G7) - Azide and BSA Free
H00005873-M02
Western Blot: Rab27a Antibody (1G7) [H00005873-M02] - Analysis of RAB27A expression in transfected 293T cell line by RAB27A monoclonal antibody (M02), clone 1G7.Lane 1: RAB27A transfected lysate(24.9 KDa).Lane 2: Non-transfected lysate.Immunohistochemistry-Paraffin: Rab27a Antibody (1G7) [H00005873-M02] - Analysis of monoclonal antibody to RAB27A on formalin-fixed paraffin-embedded human lymphoma. Antibody concentration 3 ug/ml.

Mouse Monoclonal
Species Human, Mouse, Rabbit
Applications WB, ELISA, Flow

13 Publications
AP3B1 Antibody
NBP3-38363
Immunohistochemistry: AP3B1 Antibody [NBP3-38363] - Immunohistochemistry analysis of paraffin-embedded Human breast cancer using AP3B1 Rabbit pAb at dilution of 1:100 (40x lens). High pressure antigen retrieval performed with 0.01M Citrate Bufferr (pH 6.0) prior to IHC staining.Western Blot: AP3B1 Antibody [NBP3-38363] - Western blot analysis of various lysates using AP3B1 Rabbit pAb at 1:1000 dilution.<br/>Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) at 1:10000 dilution.<br/>Lysates/proteins: 25ug per lane.<br/>Blocking buffer: 3% nonfat dry milk in TBST.<br/>Detection: ECL Basic Kit.<br/>Exposure time: 90s.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ELISA, IHC

HPS1 Antibody
NBP3-42062
Western Blot: HPS1 Antibody [NBP3-42062] - Sample: Recombinant protein.Immunohistochemistry-Paraffin: HPS1 Antibody [NBP3-42062] - DAB staining on IHC-P; Samples: Mouse Uterus Tissue; Primary Ab: 30ug/ml NBP3-42062

Rabbit Polyclonal
Species Mouse, Rat
Applications WB, IHC, IHC-P

Recombinant Human LYST GST (N-Term) Protein
H00001130-Q01
12.5% SDS-PAGE Stained with Coomassie Blue.


Species Human
Applications WB, ELISA, PA

beta-Glucuronidase/GUSB Antibody - BSA Free
NBP1-87511
Immunohistochemistry-Paraffin: beta-Glucuronidase/GUSB Antibody [NBP1-87511] - Analysis in human liver and skeletal muscle tissues using NBP1-87511 antibody. Corresponding GUSB RNA-seq data are presented for the same tissues.Western Blot: beta-Glucuronidase/GUSB Antibody [NBP1-87511] - Analysis in control (vector only transfected HEK293T lysate) and GUSB over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF, IHC

Apolipoprotein H/ApoH Antibody - BSA Free
NBP1-90046
Immunohistochemistry-Paraffin: Apolipoprotein H/ApoH Antibody [NBP1-90046] - Staining of human colon, kidney, lung and lymph node using Anti-APOH antibody NBP1-90046 (A) shows similar protein distribution across tissues to independent antibody NBP1-90045 (B).Western Blot: Apolipoprotein H/ApoH Antibody [NBP1-90046] - Analysis in Caco-2 cells transfected with control siRNA, target specific siRNA probe #1 and #2,. Remaining relative intensity is presented. Loading control: Anti-GAPDH.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF, IHC

2 Publications
WASP Antibody
NB300-996
Immunocytochemistry/Immunofluorescence: WASP Antibody [NB300-996] - Immunofluorescence analysis of paraformaldehyde fixed U2OS cells, permeabilized with 0.15% Triton. Primary incubation 1hr (10 ug/mL) followed by Alexa Fluor 488 secondary antibody (2 ug/mL), showing nuclear and cytoplasmic staining. The nuclear stain is DAPI (blue). Negative control: Unimmunized goat IgG (10 ug/mL) followed by Alexa Fluor 488 secondary antibody (2 ug/mL).Immunohistochemistry-Paraffin: WASP Antibody [NB300-996] - Staining of paraffin embedded Human Spleen. Antibody at 5 ug/mL. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

Goat Polyclonal
Species Human
Applications WB, Flow, ICC/IF

1 Publication
ACSBG1 Antibody (OTI1D8)
NBP2-02554
Western Blot: ACSBG1 Antibody (1D8) [NBP2-02554] - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ACSBG1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-ACSBG1.Immunocytochemistry/Immunofluorescence: ACSBG1 Antibody (1D8) [NBP2-02554] Staining of COS7 cells transiently transfected by pCMV6-ENTRY ACSBG1.

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

Cathepsin G Antibody - BSA Free
NBP2-33498
Immunohistochemistry-Paraffin: Cathepsin G Antibody [NBP2-33498] - Analysis in human bone marrow and cerebral cortex tissues. Corresponding Cathepsin G RNA-seq data are presented for the same tissues.Immunohistochemistry-Paraffin: Cathepsin G Antibody [NBP2-33498] - Staining of human testis shows no positivity in cells in seminiferous ducts as expected.

Rabbit Polyclonal
Species Human
Applications ICC/IF, IHC, IHC-P

6 Publications
Myeloperoxidase/MPO Antibody [Unconjugated]
AF3667
Western blot shows lysates of HL-60 human acute promyelocytic leukemia cell line, human neutrophil cells, and mouse spleen tissue. PVDF membrane was probed with 0.5 µg/mL of Goat Anti-Human/Mouse Myeloperoxidase/MPO Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3667) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (<a class=Myeloperoxidase/MPO was detected in immersion fixed mouse splenocytes using Goat Anti-Human/Mouse Myeloperoxidase/MPO Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3667) at 15 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 557-conjugated Anti-Goat IgG Secondary Antibody (red; <a class=

Goat Polyclonal
Species Human, Mouse
Applications WB, Simple Western, IHC

     3 Reviews

171 Publications
Catalase Antibody [Unconjugated]
AF3398
Western blot shows lysates of Jurkat human acute T cell leukemia cell line, Raji human Burkitt's lymphoma cell line, HeLa human cervical epithelial carcinoma cell line, NIH-3T3 mouse embryonic fibroblast cell line, A20 mouse B cell lymphoma cell line, and Rat-2 rat embryonic fibroblast cell line. PVDF membrane was probed with 0.5 µg/mL of Goat Anti-Human/Mouse/Rat Catalase Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3398) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # <a class=Simple Western lane view shows lysates of Jurkat human acute T cell leukemia cell line and Raji human Burkitt's lymphoma cell line, loaded at 0.2 mg/mL. A specific band was detected for Catalase at approximately 62 kDa (as indicated) using 5 µg/mL of Goat Anti-Human/Mouse/Rat Catalase Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3398) followed by 1:50 dilution of HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # <a class=

Goat Polyclonal
Species Human, Mouse, Rat
Applications WB, Simple Western, ICC

     3 Reviews

15 Publications
Complement C4b/d Antibody (16D2)
NB200-541
Western Blot: Complement C4b/d Antibody (16D2) [NB200-541] - Western blot analysis of C4 expression in J774.A1 (A) aand mouse PBL (B) whole cell lysates.

Rat Monoclonal
Species Mouse
Applications WB, IA, ICC/IF

12 Publications
CTLA-4 [Unconjugated]
7268-CT
Recombinant Human CTLA-4 Fc Chimera (Catalog # 7268-CT) inhibits IL-2 secretion by stimulated Jurkat human acute Tcell leukemia cells. The ED<sub>50</sub> for this effect is 0.03-0.15 μg/mL whenstimulated with 1 μg/mL Recombinant Human B7‑1/CD80 Fc Chimera (Catalog # <a class=


Species Human
Applications BA

3 Publications
LIGHT/TNFSF14 [Unconjugated]
664-LI
<P align=left>Recombinant Human LIGHT/TNFSF14 (Catalog # 664-LI) stimulates cell proliferation in HUVEC human umbilical vein endothelial cells. The ED<SUB>50</SUB> is 1-4 ng/mL.</P><p align=


Species Human
Applications BA

21 Publications
IL-2 [Unconjugated]
202-IL
As an alternative, please consider our next generation Recombinant Human IL-2 (<a class=


Species Human
Applications BA

     4 Reviews

379 Publications
VPS13B Antibody - BSA Free
NBP2-55104
Western Blot: VPS13B Antibody [NBP2-55104] - Analysis in human ovary tissue.Immunocytochemistry/Immunofluorescence: VPS13B Antibody [NBP2-55104] - Staining of human cell line U-2 OS shows localization to cell junctions. Antibody staining is shown in green.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF

     1 Review

Tyrosinase Antibody (JA52-11)
NBP2-67232
Western Blot: Tyrosinase Antibody (JA52-11) [NBP2-67232] - Western blot analysis of Tyrosinase on B16F1 cell lysates. Proteins were transferred to a PVDF membrane and blocked with 5% BSA in PBS for 1 hour at room temperature. The primary antibody (1/500) was used in 5% BSA at room temperature for 2 hours. Goat Anti-Rabbit IgG - HRP Secondary Antibody (HA1001) at 1:200,000 dilution was used for 1 hour at room temperature.Immunocytochemistry/Immunofluorescence: Tyrosinase Antibody (JA52-11) [NBP2-67232] - Staining Tyrosinase in B16F1 cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Rabbit Monoclonal
Species Human, Mouse
Applications WB, ICC/IF, IHC

LAMP-1/CD107a Antibody - BSA Free
NB120-19294
Western Blot: LAMP-1/CD107a Antibody [NB120-19294] - Analysis of 20 ug of HeLa cell lysate and 5 ul of Molecular Weight Protein Ladder per well.Immunocytochemistry/Immunofluorescence: LAMP-1/CD107a Antibody [NB120-19294] - Cathepsin D (CathD) expression and localization in primary neurons. Colocalization of transfected CathD with LAMP-1/CD107a. CathD transfected neurons were examined by co-immunostaining of LAMP-1/CD107a and CathD. Yellow colored cytoplasmic spots are indicative of co-localization of transfected cathepsins and LAMP-1/CD107a. Scale bar = 10 micron. Image collected and cropped by CiteAb from the following publication (https://molecularneurodegeneration.biomedcentral.com/articles/10.1186/1750-1326-6-37), licensed under a CC-BY license.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

     2 Reviews

38 Publications

Related Genes

Chediak-higashi Syndrome has been researched against:

Related Pathways

Chediak-higashi Syndrome has been linked to:

Related Diseases

Chediak-higashi Syndrome has been studied in relation to diseases such as:

Related PTMs

Chediak-higashi Syndrome has been studied in relation to posttranslational modifications (PTMs) including:

Alternate Names

Chediak-higashi Syndrome is also known as chediak-higashi syndrome, chediak higashi syndrome, chs, oculocutaneous albinism with leukocyte defect, chediak-steinbrinck-higashi syndrome, chediak - steinbrinck anomaly.