WRCH1 Products

Description

Function: Acts upstream of PAK1 to regulate the actin cytoskeleton, adhesion turnover and increase cell migration. Stimulates quiescent cells to reenter the cell cycle. Has no detectable GTPase activity but its high intrinsic guanine nucleotide exchange activity suggests it is constitutively GTP-bound.; Subcellular location: Cell membrane; Lipid-anchor; Cytoplasmic side. Golgi apparatus membrane; Lipid-anchor. Cell junction > focal adhesion. Cell projection > podosome. Note: Localizes to podosomes in SRC-transformed cells.; Tissue specificity: Ubiquitously expressed in all tissues examined. Expressed at high levels in the stomach, small intestine, brain, skeletal muscle and placenta.

Bioinformatics

Entrez	58480 Human 69581 Mouse
Uniprot	NP_067028 Human Q7L0Q8 Human
Product By Gene ID	58480
Alternate Names	ARHU CDC42L1GTP-binding protein-like 1 DJ646B12.2 fJ646B12.2 FLJ10616,2310026M05Rik G28K GTP-binding protein like 1 GTP-binding protein SB128 hG28K ras homolog gene family, member U ras-like gene family member U Rho GTPase-like protein ARHU rho-related GTP-binding protein RhoU Ryu GTPase Wnt-1 responsive Cdc42 homolog 1 WRCH-1 WRCH1CDC42-like GTPase 1

Research Areas for WRCH1

Find related products by research area and learn more about each of the different research areas below.

Cell Biology
Signal Transduction