V-type proton ATPase subunit F Products

Description

V-type proton ATPase subunit F encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c", and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is the V1 domain F subunit protein. [provided by RefSeq]

Bioinformatics

Entrez	9296 Human
Uniprot	NM_004231 Human NP_004222 Human NP_004222.2 Human Q16864 Human
Product By Gene ID	9296
Alternate Names	ATP6S14adenosinetriphosphatase 14k chain ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F H(+)-transporting two-sector ATPase, 14kD subunit MGC117321 MGC126037 MGC126038 vacuolar ATP synthase subunit F vacuolar proton pump F subunit Vacuolar proton pump subunit F VATFATPase, vacuolar, 14 kD V-ATPase 14 kDa subunit V-ATPase F subunit V-ATPase subunit F Vma7 V-type proton ATPase subunit F