UbcH5c/UBE2D3 Products

Description

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase. Multiple spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been determined.

Bioinformatics

Entrez	7323 Human
Uniprot	AAH03395 Human NM_181887 Human NM_181893 Human NP_003331 Human NP_871615 Human NP_871617 Human NP_871618 Human NP_871619 Human NP_871620 Human NP_871622 Human P61077 Human
Product By Gene ID	7323
Alternate Names	E2(17)KB 3 E2(17)KB3 EC 6.3.2.19 MGC43926 MGC5416 UBC4/5 UBC5C UbcH5C UBCH5C Ubiquitin carrier protein D3 ubiquitin-conjugating enzyme E2 D3 Ubiquitin-conjugating enzyme E2(17)KB 3 Ubiquitin-conjugating enzyme E2-17 kDa 3 ubiquitin-conjugating enzyme E2D 3 (homologous to yeast UBC4/5) ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast) Ubiquitin-protein ligase D3