UAP56 Products

Description

UAP56 encodes a member of the DEAD box family of RNA-dependent ATPases that mediate ATP hydrolysis during pre-mRNA splicing. The encoded protein is an essential splicing factor required for association of U2 small nuclear ribonucleoprotein with pre-mRNA, and also plays an important role in mRNA export from the nucleus to the cytoplasm. A cluster of genes, BAT1-BAT5, is localized in the vicinity of the genes for TNF alpha and TNF beta. These genes are all within the human major histocompatibility complex class III region. Mutations in this gene may be associated with rheumatoid arthritis. Alternatively spliced transcript variants encoding the same protein have been described.

Bioinformatics

Entrez	7919 Human
Uniprot	AAH00361 Human NM_004640 Human NM_080598 Human NP_004631 Human
Product By Gene ID	7919
Alternate Names	56 kDa U2AF65-associated protein ATP-dependent RNA helicase p47 DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B DEAD box protein UAP56 EC 3.6.4.13 HLA-B associated transcript 1 HLA-B-associated transcript 1 protein spliceosome RNA helicase BAT1 UAP56D6S81EBAT1nuclear RNA helicase (DEAD family)