Species: Hu, Mu, Rt, Bv, Ca, Xp, Ze
Applications: WB, ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu, Mu
Applications: WB, ELISA, ICC/IF, IHC, CyTOF-ready
Host: Mouse Monoclonal
Species: Hu, Mu
Applications: WB, ELISA, IHC, CyTOF-ready
Host: Mouse Monoclonal
Species: Hu
Applications: WB
Species: Hu
Applications: WB
Species: Hu
Applications: PAGE
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Description
UAP56 encodes a member of the DEAD box family of RNA-dependent ATPases that mediate ATP hydrolysis during pre-mRNA splicing. The encoded protein is an essential splicing factor required for association of U2 small nuclear ribonucleoprotein with pre-mRNA, and also plays an important role in mRNA export from the nucleus to the cytoplasm. A cluster of genes, BAT1-BAT5, is localized in the vicinity of the genes for TNF alpha and TNF beta. These genes are all within the human major histocompatibility complex class III region. Mutations in this gene may be associated with rheumatoid arthritis. Alternatively spliced transcript variants encoding the same protein have been described.
Bioinformatics
Entrez |
Human |
Uniprot |
Human Human Human Human |
Product By Gene ID |
7919 |
Alternate Names |
- 56 kDa U2AF65-associated protein
- ATP-dependent RNA helicase p47
- DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B
- DEAD box protein UAP56
- EC 3.6.4.13
- HLA-B associated transcript 1
- HLA-B-associated transcript 1 protein
- spliceosome RNA helicase BAT1
- UAP56D6S81EBAT1nuclear RNA helicase (DEAD family)
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