Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB, ELISA, KD
Host: Mouse Monoclonal
Species: Hu
Applications: WB
Species: Hu
Applications: PAGE
Species: Hu
Applications: AC
Description
Tissue specific transplantation antigen P35B is a NADP(H)-binding protein. It catalyze the two-step epimerase and the reductase reactions in GDP-D-mannose metabolism, converting GDP-4-keto-6-D-deoxymannose to GDP-L-fucose. GDP-L-fucose is the substrate of several fucosyltransferases involved in the expression of many glycoconjugates, including blood group ABH antigens and developmental adhesion antigens. Mutations in this gene may cause leukocyte adhesion deficiency, type II.
Bioinformatics
| Entrez |
Human
|
| Uniprot |
Human
Human
Human
Human
|
| Product By Gene ID |
7264 |
| Alternate Names |
- EC 1.1.1.271
- FX
- GDP-4-keto-6-deoxy-D-mannose epimerase-reductase
- GDP-4-keto-6-deoxy-D-mannose-3,5-epimerase-4-reductase
- GDP-L-fucose synthase
- P35B
- Protein FX
- Red cell NADP(H)-binding protein
- SDR4E13-5 epimerase/4-reductase
- short chain dehydrogenase/reductase family 4E, member 1
- Short-chain dehydrogenase/reductase family 4E member 1
- tissue specific transplantation antigen 3
- tissue specific transplantation antigen P35B
- Tissue-specific transplantation antigen-3
|
