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TRPC6 Products

TRPC6 Antibody - BSA Free
TRPC6 Antibody - BSA Free
NBP1-31008
Image 1 of 3
Species: Hu, Mu, Bv
Applications: WB, IHC
Host: Rabbit Polyclonal

Description

The protein encoded by the TRPC6 gene creates receptor-activated cation permeant calcium channels in the cell membrane. Isoform 1 is 931 amino acids in length and is approximately 106 kDa, while isoform 2 is 815 amino acids in lenth at around 93 kDA. Isoform 3 is 876 amino acids long and is just over 100 kDA. Focal segmental glomerulosclerosis 2 (FSGS2) is caused by deficits in the TRPC6 gene. This gene has been linked to diseases such as cystic fibrosis, gigantism, hypertension, kidney disease, glomerulosclerosis, pyloric stenosis, diencephalic neoplasm, premature ovarian failure, and hepatopulmonary syndrome. The TRPC6 gene interacts with MX1, ORAI1, NPHS1, NPHS2, and FYN genes in pathways that monitor sodium as well as calcium channels, EPO signaling pathway, G alpha (q) signaling events, signal transduction, and platelet homeostasis.

Bioinformatics

Entrez Mouse
Human
Rat
Uniprot Human
Human
Human
Rat
Human
Product By Gene ID 7225
Alternate Names
  • FLJ11098
  • FSGS2
  • short transient receptor potential channel 6
  • transient receptor potential cation channel, subfamily C, member 6
  • Transient receptor protein 6
  • TRP-6
  • TRP6FLJ14863
  • TrpC6

Research Areas for TRPC6

Find related products by research area and learn more about each of the different research areas below.

Signal Transduction