TRIM5 alpha Products

Description

TRIM5-alpha is a protein that is found in the cells of many mammals and fends of various retrovirus infections. It protects monkeys from infection with HIV-1, and humans from infection with some other viruses. If a retrovirus has entered a cell, it needs to shed its capsid in order to reversely transcribe its genes, so that they can be expressed by the host cell. It is believed that TRIM5 alpha, which is present in the cytoplasm, somehow recognizes the capsid and blocks its shedding, thereby stopping the virus in its tracks. It thus represents an intracellular defense completely separate from the rest of the body's immune system.

Bioinformatics

Entrez	85363 Human
Uniprot	NP_149023 (Human) Human NP_149023 Human Q9C035 Human
Product By Gene ID	85363
Alternate Names	EC 6.3.2 EC 6.3.2.- RING finger protein 88 RNF88tripartite motif protein TRIM TRIM5alpha tripartite motif containing 5 tripartite motif protein TRIM5 tripartite motif-containing 5 tripartite motif-containing protein 5

Research Areas for TRIM5 alpha

Find related products by research area and learn more about each of the different research areas below.

Immunology
Lipid and Metabolism
Virology, Bacteria and Parasites
Zinc Finger