Species: Hu, Mu, Pm-Or
Applications: WB, IHC, IP, KD
Host: Rabbit Polyclonal
Species: Hu, Mu
Applications: WB
Host: Goat Polyclonal
Species: Hu, Mu
Applications: WB, ICC/IF, IHC, IP
Host: Rabbit Monoclonal
Species: Hu
Applications: WB, ELISA, MA, PAGE, AP
Species: Hu
Applications: AC
Description
MED1, also referred to as Mediator Complex Subunit 1, localizes to the nucleus and is involved in DNA repair. MED1 is able to remove Uracil in Uracil-Guanine mismatched base-pairs. Current research on MED1 is being performed in relation to several diseases and disorders including ovarian cancer, thyroiditis, breast cancer, Parkinson's disease, influenza, alopecia, Williams syndrome, diabetes mellitus, ataxia telangiectasia, thyroid cancer, Alzheimer's disease and rickets. MED1 has also been shown to have interactions with p53, MED15, RARA, KAT2A, and CDK8 in pathways such as fatty acid, triacylglycerol, and ketone body metabolism and the PPAR pathway.
Bioinformatics
Uniprot |
Human |
Product By Gene ID |
5469 |
Alternate Names |
- Activator-recruited cofactor 205 kDa component
- ARC205
- CRSP1TRIP2
- CRSP200p53 regulatory protein RB18A
- DRIP230PPAR-binding protein
- mediator complex subunit 1DRIP205
- mediator of RNA polymerase II transcription subunit 1
- PBPPPARGBP
- Peroxisome proliferator-activated receptor-binding protein
- PPAR binding protein
- PPARBPMGC71488
- PPARG binding protein
- RB18ATR-interacting protein 2
- Thyroid hormone receptor-associated protein complex 220 kDa component
- thyroid hormone receptor-associated protein complex component TRAP220
- thyroid receptor interacting protein 2
- Thyroid receptor-interacting protein 2
- Trap220
- TRAP220TRIP-2
- vitamin D receptor-interacting protein 230 kD
- Vitamin D receptor-interacting protein complex component DRIP205
|
Research Areas for TRAP220/MED1
Find related products by research area and learn more about each of the different research areas below.
Cancer