Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IP, KO
Host: Mouse Monoclonal
Species: Hu
Applications: WB, IHC, IP
Host: Rabbit Polyclonal
Species: Hu
Applications: WB, IHC, IP
Host: Rabbit Polyclonal
Species: Hu
Applications: PAGE
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Description
Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation.
Bioinformatics
Entrez |
Human |
Uniprot |
Human Human |
Product By Gene ID |
8148 |
Alternate Names |
- 68kDa
- hTAFII68
- Npl3
- RBP56TAFII68
- RNA-binding protein 56
- TAF(II)68
- TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor
- TAF2NRBP56/CSMF fusion
- TATA box binding protein (TBP)-associated factor, RNA polymerase II, N, 68kD(RNA-binding protein 56)
- TATA box-binding protein-associated factor 2N (RNA-binding protein 56)
- TATA-binding protein-associated factor 2N
- TBP-associated factor 15,68 kDa TATA-binding protein-associated factor
|
Research Areas for TAF15
Find related products by research area and learn more about each of the different research areas below.
DNA RepairNeuroscience