SYK Products

Description

Syk (72 kDa) is a non-receptor protein tyrosine kinase that plays an important role in immune receptor signal transduction and is implicated in endothelial cell functions, including cell growth and migration. SYK is a positive effector of BCR stimulated responses. It couples the B cell antigen receptor (BCR) to the mobilization of calcium ions either through a phosphoinositide 3 kinase dependent pathway, when not phosphorylated on tyrosines of the linker region, or through a phospholipase C gamma dependent pathway, when phosphorylated on Tyr 342 and Tyr 346. Thus the differential phosphorylation of SYK can determine the pathway by which BCR is coupled to the regulation of intracellular calcium ions.

Bioinformatics

Entrez	20963 Mouse 25155 Rat 2534 Human 6850 Human
Uniprot	AAH01645 Human NM_003177 Human NP_003168 Human NP_003168.2 Human P43405 Human
Product By Gene ID	6850
Alternate Names	DKFZp313N1010 EC 2.7.10 EC 2.7.10.2 FLJ25043 spleen tyrosine kinaseFLJ37489 tyrosine-protein kinase SYK

Research Areas for SYK

Find related products by research area and learn more about each of the different research areas below.

Immunology
Innate Immunity
Mast Cell Markers
Phospho-Specific
Protein Kinase