SRM Products

Description

The Arp2/3 protein complex has been implicated in the control of actin polymerization in cells. The human complex consists of seven subunits which include the actin related proteins Arp2 and Arp3, and five others referred to as p41-Arc, p34-Arc, p21-Arc, p20-Arc, and p16-Arc (p omplex) (1). These proteins localize in the cytoplasm of fibroblasts that lack lamellipodia, but are enriched in lamellipodia on stimulation with serum or platelet-derived growth factor. A dynamic role for this complex in the organization of the actin cytoskeleton has been suggested (2). p16-Arc has been found to be a globular alpha-helical subunit (3).

Bioinformatics

Entrez	6723 Human
Uniprot	AAH00309 Human NM_003132 Human NP_003123 Human NP_003123.2 Human P19623 Human
Product By Gene ID	6723
Alternate Names	EC 2.5.1 EC 2.5.1.16 Putrescine aminopropyltransferase SPDSY spermidine synthase spermidine synthase-1 SPS1PAPT SRML1

Research Areas for SRM

Find related products by research area and learn more about each of the different research areas below.

Protein Kinase