Species: Hu
Applications: WB
Host: Goat Polyclonal
Species: Hu, Mu
Applications: WB, IP
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt
Applications: IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB, ELISA, MA, AP
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Description
SOS2 (son of sevenless homolog 2) is a human paralog of the Drosophila SOS gene. Drosophila SOS was originally identified as a gene that functioned downstream of the sevenless gene in the Ras/MAP kinase signaling pathway. SOS and its paralogs, SOS1 and SOS2, function as guanine nucleotide exchange factors that act on Ras-GTPases to cause release of GDP in exchange for GTP. Although targeted disruption of SOS1 results in embryonic lethality, disruption of SOS2 does not have any effects on mouse development, growth, or fertility.
Bioinformatics
| Entrez |
Human
|
| Uniprot |
Human
Human
|
| Product By Gene ID |
6655 |
| Alternate Names |
- FLJ25596
- guanine nucleotide exchange factor
- guanine nucleotide releasing factor
- son of sevenless (Drosophilia) homolog 2
- son of sevenless homolog 2 (Drosophila)
- son of sevenless homolog 2
- SOS-2
|
Research Areas for SOS2
Find related products by research area and learn more about each of the different research areas below.
Breast CancerCancer
![Western Blot SOS2 Antibody [Unconjugated]](http://images.novusbio.com/fullsize2/SOS2_AF6260_Western_Blot_9542.jpg)
