Species: Mu
Applications: WB, Flow, IHC, CyTOF-ready
Host: Sheep Polyclonal
Species: Hu
Applications: WB, ELISA, Flow, IHC
Host: Mouse Monoclonal
Species: Hu
Applications: Flow, IP
Host: Mouse Monoclonal
Species: Mu
Applications: ELISA
Host: Rabbit Monoclonal
Species: Mu
Applications: ELISA
Species: Hu
Applications: WB
Species: Hu
Applications: Bioactivity
Species: Mu
Applications: Bioactivity
Species: Hu
Applications: AC
Description
Semaphorins are neuronal chemorepellants that direct pioneering neurons during nervous system development. CD100, a 150 kDa homodimer, is a novel semaphorin that induces B cells to aggregate and improves their viability in vitro. CD100 modifies CD40-CD40L B cell signaling by augmenting B cell aggregation and survival and down regulating CD23 expression. CD72 is a lymphocyte receptor for the class IV semaphorin CD100, which is involved in regulating B cell signaling. CD100 is expressed on resting and PHA stimulated T cells. The protein is weakly expressed on NK cells, EBV transformed B cells, monocytes and tumor/peripheral blood T cell lines, and at higher density on activated T cells and B cells.
Bioinformatics
| Entrez |
Human
|
| Uniprot |
Human
Human
Human
|
| Product By Gene ID |
10507 |
| Alternate Names |
- A8
- CD100 antigen
- CD100M-sema-G
- coll-4
- FLJ33485
- FLJ34282
- FLJ39737
- FLJ46484
- immunoglobulin domain (Ig), transmembrane domain (TM) and shortcytoplasmic domain, 4D
- MGC169138
- MGC169141
- sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and shortcytoplasmic domain, (semaphorin) 4D
- semaphorin-4D
|
Research Areas for Semaphorin 4D/CD100
Find related products by research area and learn more about each of the different research areas below.
ApoptosisCD MarkersImmunology
![Flow Cytometry Semaphorin 4D/CD100 Antibody [Unconjugated]](http://images.novusbio.com/fullsize2/Semaphorin_4D_AF5235_Flow_Cytometry_8267.jpg)
![Sandwich ELISA Semaphorin 4D/CD100 Antibody Pair [HRP]](http://images.novusbio.com/fullsize/Semaphorin-4D-CD100-Antibody-Pair-[HRP]-Sandwich-ELISA-NBP2-79597-img0001.jpg)
![Binding Activity Semaphorin 4D/CD100 [Unconjugated]](http://images.novusbio.com/fullsize2/Semaphorin_4D_5235S4B_3251.jpg)
![Immunohistochemistry Semaphorin 4D/CD100 Antibody [Unconjugated]](http://images.novusbio.com/fullsize2/Semaphorin_4D_AF5235_Immunohistochemistry_24184.jpg)
