Species: Hu
Applications: WB
Host: Sheep Polyclonal
Species: Hu, Mu, Rt, Bv
Applications: WB, ELISA, ICC/IF
Host: Rabbit Polyclonal
Species: Hu
Applications: WB, ELISA, Flow
Host: Goat Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: WB, ELISA, MA, AP
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Description
RNF8 is encoded by this gene contains a RING finger motif and a FHA domain. This protein has been shown to interact with several class II ubiquitin-conjugating enzymes (E2), including UBE2E1/UBCH6, UBE2E2, and UBE2E3, and may act as an ubiquitin ligase (E3) in the ubiquitination of certain nuclear proteins. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
Bioinformatics
| Entrez |
Rat
Mouse
Human
|
| Uniprot |
Human
Human
Human
Human
Human
|
| Product By Gene ID |
9025 |
| Alternate Names |
- C3HC4-type zinc finger protein
- EC 6.3.2
- EC 6.3.2.-
- FLJ12013
- KIAA0646UBC13/UEV-interacting ring finger protein
- ring finger protein (C3HC4 type) 8
- ring finger protein 8E3 ubiquitin-protein ligase RNF8
|
Research Areas for RNF8
Find related products by research area and learn more about each of the different research areas below.
Stem Cell MarkersZinc Finger
Related RNF8 Blog Posts
Check out the latest blog posts on RNF8.
53BP1 - DNA damage is no fun
The 53BP1 (p53 binding protein 1) was initially believed to be a p53 transcriptional enhancing partner, but it has now been established as an ataxia telangiectasia mutated (ATM) substrate. As a late DNA damage response (DDR) marker, 53BP1 appears duri... Read more.
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Read more RNF8 related blogs.
