RNF34 Products

Description

The protein encoded by the RNF34 gene contains a RINF finger, a motif known to be involved in protein-protein andprotein-DNA interactions. This protein interacts with DNAJA3/hTid-1, which is a DnaJ protein reported to function as amodulator of apoptosis. Overexpression of this gene in Hela cells was shown to confer the resistance to TNF-alphainduced apoptosis, suggesting an anti-apoptotic function of this protein. This protein can be cleaved by caspase-3during the induction of apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have beenreported. (provided by RefSeq)

Bioinformatics

Entrez	282845 Rat 80196 Human 80751 Mouse
Uniprot	AAH07826 Human NM_025126 Human NP_079402 Human NP_919247 Human NP_919247.1 Human Q969K3 Human
Product By Gene ID	80196
Alternate Names	CARP1 Caspase regulator CARP1 Caspases-8 and -10-associated RING finger protein 1 E3 ubiquitin-protein ligase RNF34 EC 6.3.2 EC 6.3.2.- FLJ21786 FYVE-RING finger protein Momo hRFI Human RING finger homologous to inhibitor of apoptosis protein RFI RIF RIFF ring finger protein 34CARP-1 RING finger protein RIFF

Research Areas for RNF34

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Apoptosis