RIZ1 Products

Description

RIZ1 (Retinoblastoma proteininteracting zinc finger), also known as PRDM2, is a nuclear protein containing 8 zinc finger motifs. RIZ1 contains a PR domain that may function as protein binding interface in the regulation of chromatin-mediated gene expression. RIZ 1 acts as a tumor suppressor, and RIZ 1 inactivation is common in many types of human cancers, including neuroendocrine, breast, liver, colon, skin, and lymphoid tumors. Similarly, RIZ1 over-expression in breast cancer cells caused cell cycle arrest in G2-M and apoptosis. RIZ1 is highly expressed in human retinoblastoma cells and at low levels in all other human cell lines.

Bioinformatics

Entrez	7799 Human
Uniprot	NP_036363 Human
Product By Gene ID	7799
Alternate Names	EC 2.1.1.43 GATA-3 binding protein G3B GATA-3-binding protein G3B KMT8PR domain-containing protein 2 Lysine N-methyltransferase 8 MTB-ZFHUMHOXY1 PR domain containing 2, with ZNF domain PR domain zinc finger protein 2 retinoblastoma protein-binding zinc finger protein Retinoblastoma protein-interacting zinc finger protein RIZ1 RIZ2 RIZMTE-binding protein Zinc finger protein RIZ zinc-finger DNA-binding protein

Research Areas for RIZ1

Find related products by research area and learn more about each of the different research areas below.

Breast Cancer
Chromatin Research