RhoC Products

Description

RhoC encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The protein encoded by this gene is prenylated at its C-terminus, and localizes to the cytoplasm and plasma membrane. It is thought to be important in cell locomotion. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Bioinformatics

Entrez	11853 Mouse 295342 Rat 389 Human
Uniprot	AAH07245 Human NM_001042679 Human NM_175744 Human NM_175744.4 Human NP_001036143 Human NP_001036144 Human NP_786886 Human NP_786886.1 Human P08134 Human Q62159 Mouse
Product By Gene ID	389
Alternate Names	ARH9ARHCRho cDNA clone 9 h9 H9 MGC1448 MGC61427 oncogene RHO H9 ras homolog gene family, member C RAS-related homolog 9 rhoC GTPase RhoC RHOH9 rho-related GTP-binding protein RhoC small GTP binding protein RhoC

Research Areas for RhoC

Find related products by research area and learn more about each of the different research areas below.

Signal Transduction

Related RhoC Blog Posts

Check out the latest blog posts on RhoC.

Suppressing breast cancer metastasis: The role of hypoxia-induced RhoB expression and activation By Jamshed Arslan, Pharm. D., PhD. The Ras homologous (Rho) GTPase family of signaling molecules has over 20 members, which typically cycle between active (GTP-bound) and inactive (GDP-bound) states. These small GTPa...    Read more.

Read more RhoC related blogs.