RGS3 Products

Description

RGS 3 (Regulator of G protein Signaling 3) is a 519 residue protein that is widely expressed in many tissues and cells. The protein contains an RGS domain near the carboxy terminus that serves as a GTPase activating protein (GAP). RGS 3 negatively regulates the activation of Gialpha and G alpha q. A truncated RGS 3 (RGS 3T), with its N-terminal 313 residues removed, has been shown to negatively regulate acenylyl cyclase and PLC. RGS 3T may be localized in the nucleus and RGS 3 is found in cytoplasm. Translocation to the membrane is important for the RGS proteins to interact with heterotrimeric G proteins.

Bioinformatics

Entrez	5998 Human
Uniprot	AAH18072 Human NM_021106 Human NM_130795 Human NM_134427 Human NM_144489 Human NP_602299 Human NP_602299.1 Human NP_652759 Human P49796 Human P49796-4 Human
Product By Gene ID	5998
Alternate Names	C2PA FLJ20370 FLJ31516 FLJ90496 PDZ-RGS3 regulator of G-protein signaling 3 regulator of G-protein signalling 3 RGP3

Research Areas for RGS3

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Signal Transduction