Species: Hu, Mu, Rt
Applications: WB, ELISA, Flow, ICC/IF, IHC
Host: Mouse Monoclonal
Species: Hu, Mu, Rt
Applications: WB, IHC
Host: Mouse Monoclonal
Species: Hu, Mu, Rt, Fi, Xp
Applications: WB, Simple Western, ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: WB, ELISA, MA, AP
Description
RBBP7 antibody, also known as RbAp46 (Retinoblastoma protein associated protein 46), is a nuclear protein that has been shown to interact directly with retinoblastoma protein and is a component of the mSin3 corepressor complex, as are the histone deacetylase proteins (HDACs). It shares about 75% sequence identity with the closely related RbAp48, and appears to be functionally related to the yeast MSI1 protein in that overexpression of RbAp46 suppresses heat shock sensitivity in a RAS pathway dependent manner. RBBP7 has also been demonstrated to be up-regulated by the Wilms' tumor suppressor gene product, WT1. In addition, cells transfected with this antibody have shown strong inhibition of growth.
Bioinformatics
| Entrez |
Human
|
| Uniprot |
Human
Human
Human
|
| Product By Gene ID |
5931 |
| Alternate Names |
- G1/S transition control protein-binding protein RbAp46
- Histone acetyltransferase type B subunit 2
- histone-binding protein RBBP7
- MGC138867
- Nucleosome-remodeling factor subunit RBAP46
- RBAP46
- RbAp46
- RBBP-7
- retinoblastoma binding protein 7
- Retinoblastoma-binding protein 7MGC138868
- Retinoblastoma-binding protein p46
- retinoblastoma-binding protein RbAp46
|
