Species: Hu, Mu, Rt
Applications: WB, ELISA, ICC/IF, IHC, IP, KD
Host: Mouse Monoclonal
Species: Hu
Applications: WB
Host: Mouse Monoclonal
Species: Hu
Applications: WB, IP, KO
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: WB, ELISA, MA, PAGE, AP
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Description
RAD18 is encoded by this gene is highly similar to S. cerevisiae DNA damage repair protein Rad18. Yeast Rad18 functions through its interaction with Rad6, which is an ubiquitin-conjugating enzyme required for post-replication repair of damaged DNA. Similar to its yeast counterpart, this protein is able to interact with the human homolog of yeast Rad6 protein through a conserved ring-finger motif. Mutation of this motif results in defective replication of UV-damaged DNA and hypersensitivity to multiple mutagens.
Bioinformatics
| Entrez |
Human
|
| Uniprot |
Human
Human
Human
|
| Product By Gene ID |
56852 |
| Alternate Names |
- EC 6.3.2.-
- hHR18
- hRAD18
- postreplication repair protein hRAD18p
- Postreplication repair protein RAD18
- RAD18 homolog (S. cerevisiae)
- RAD18, S. cerevisiae, homolog
- RING finger protein 73
- RNF73E3 ubiquitin-protein ligase RAD18
|
