PSMA4 Products

Description

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Bioinformatics

Entrez	26441 Mouse 29671 Rat 5685 Human
Uniprot	AAH05361 Human NM_002789 Human NP_001096137 Human NP_002780.1 Human P25789 Human Q567Q5 Human
Product By Gene ID	5685
Alternate Names	HC9EC 3.4.25.1 HsT17706 Macropain subunit C9 MGC12467 MGC24813 Multicatalytic endopeptidase complex subunit C9 proteasome (prosome, macropain) subunit, alpha type, 4 Proteasome component C9 proteasome subunit alpha type-4 proteasome subunit HC9 Proteasome subunit L PSC9MGC111191