Protein Phosphatase 1 beta Products

Description

Protein phosphatase 1 (PP1) is a major eukaryotic protein serine/threonine phosphatase that regulates an enormous variety of cellular functions through the interaction of its catalytic subunit (PP1c) with over fifty different established or putative regulatory subunits (1). The coordinated and reciprocal action of serine/threonine (Ser/Thr) protein kinases and phosphatases produces transient phosphorylation, a fundamental regulatory mechanism for many biological processes. PP1 is ubiquitously distributed and regulates a broad range of cellular functions, including glycogen metabolism, cell-cycle progression and muscle relaxation. PP1 has evolved effective catalytic machinery but lacks substrate specificity. Substrate specificity is conferred upon PP1 through interactions with a large number of regulatory subunits (2). It has been shown that PP1 determines the efficacy of learning and memory by limiting acquisition and favoring memory decline. When PP1 is genetically inhibited during learning, short intervals between training episodes are sufficient for optimal performance (3).

Bioinformatics

Entrez	19046 Mouse 25594 Rat 5500 Human
Uniprot	NM_002709 Human NM_206876 Human NP_002700 Human NP_002700.1 Human P62140 Human
Product By Gene ID	5500
Alternate Names	EC 3.1.3.16 EC 3.1.3.53 MGC3672 PP1beta PP-1Bprotein phosphatase 1, catalytic subunit, delta isoform PPP1CD protein phosphatase 1, catalytic subunit, beta isoform protein phosphatase 1, catalytic subunit, beta isozyme protein phosphatase 1-beta protein phosphatase 1-delta serine/threonine protein phosphatase PP1-beta catalytic subunit serine/threonine-protein phosphatase PP1-beta catalytic subunit

Research Areas for Protein Phosphatase 1 beta

Find related products by research area and learn more about each of the different research areas below.

Cancer
Lipid and Metabolism
Protein Phosphatase

Related Protein Phosphatase 1 beta Blog Posts

Check out the latest blog posts on Protein Phosphatase 1 beta.

Myc-tag: The "Monkey Wrench" of Proteomic Tools c-Myc is a well-characterized transcription factor encoded by the c-Myc gene on human chromosome 8q24. This cellular proto-oncogene, also known as p62, is commonly activated in a variety of tumor cells and plays a crucial role in cellular proliferatio...    Read more.

Read more Protein Phosphatase 1 beta related blogs.