Species: Hu, Mu
Applications: WB, Func
Host: Rabbit Polyclonal
Species: Hu, Bv
Applications: WB, IHC, IP (-)
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt
Applications: ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: WB
Species: Hu
Applications: WB, ELISA, MA, AP
Species: Hu
Applications: AC
Description
PRMT6 severely impairs the function of HIV-1 Rev. PRMT6 is a protein arginine N-methyltransferase, and catalyzes the sequential transfer of a methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins to form methylated arginine derivatives and S-adenosyl-L-homocysteine. Protein arginine methylation is a prevalent post-translational modification in eukaryotic cells that has been implicated in signal transduction, the metabolism of nascent pre-RNA, and the transcriptional activation processes. In addition, PRMT6 displays automethylation activity; it is the first PRMT to do so. PRMT6 has been shown to act as a restriction factor for HIV replication.
Bioinformatics
| Entrez |
Human
|
| Uniprot |
Human
Human
Human
Human
Human
|
| Product By Gene ID |
55170 |
| Alternate Names |
- EC 2.1.1.-
- EC 2.1.1.125
- FLJ10559
- FLJ51477
- Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 6
- Histone-arginine N-methyltransferase PRMT6
- HMT1 hnRNP methyltransferase-like 6 (S. cerevisiae)
- HMT1 hnRNP methyltransferase-like 6
- HRMT1L6
- protein arginine methyltransferase 6
- protein arginine N-methyltransferase 6
|
Related PRMT6 Blog Posts
Check out the latest blog posts on PRMT6.
PRMT6: One Function, Many Roles
Protein arginine methylation is a prevalent posttranslational modification in eukaryotic cells. It regulates RNA processing, trafficking and nascent pre-RNA metabolism, receptor-mediated signal transduction, and transcriptional activation processes. P... Read more.
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Read more PRMT6 related blogs.
