PRMT6 Antibody - BSA Free

PRMT6 severely impairs the function of HIV-1 Rev. PRMT6 is a protein arginine N-methyltransferase, and catalyzes the sequential transfer of a methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins to form methylated arginine derivatives and S-adenosyl-L-homocysteine. Protein arginine methylation is a prevalent post-translational modification in eukaryotic cells that has been implicated in signal transduction, the metabolism of nascent pre-RNA, and the transcriptional activation processes. In addition, PRMT6 displays automethylation activity; it is the first PRMT to do so. PRMT6 has been shown to act as a restriction factor for HIV replication.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: IHC-P.

Showing Publications 1 - 3 of 3.

Publications using NB110-40713	Applications	Species
Yang Y, Wang Z, Long S et al. High PRMT6 expression Associated With Prognosis and Immune Infiltration in Glioma Research Square 2021-02-10 (IHC-P, Human)	IHC-P	Human
Neault M, Mallette FA, Vogel G et al. Ablation of PRMT6 reveals a role as a negative transcriptional regulator of the p53 tumor suppressor. Nucleic Acids Res 2012-10-01 [PMID: 22904064]
Iberg AN, Espejo A, Cheng D et al. Arginine methylation of the histone H3 tail impedes effector binding. J Biol Chem 2008-02-01 [PMID: 18077460]

Array NB110-40713

• PRMT6 Antibodies
• PRMT6 Lysates
• PRMT6 Proteins