PRKAG2 Products

Description

AMP-activated protein kinase (AMPK) is a heterotrimeric protein composed of a catalytic alpha subunit, a noncatalytic beta subunit, and a noncatalytic regulatory gamma subunit. Various forms of each of these subunits exist, encoded by different genes. AMPK is an important energy-sensing enzyme that monitors cellular energy status and functions by inactivating key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This gene is a member of the AMPK gamma subunit family and encodes a protein with four cystathionine beta-synthase domains. Mutations in this gene have been associated with ventricular pre-excitation (Wolff-Parkinson-White syndrome), progressive conduction system disease and cardiac hypertrophy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq]

Bioinformatics

Entrez	51422 Human
Uniprot	AAH20540 Human NM_016203 Human NP_001035723 Human NP_057287 Human NP_077747.1 Human Q9UGJ0 Human
Product By Gene ID	51422
Alternate Names	AAKG AAKG2 CMH6AMPK subunit gamma-2 H91620pAMPK gamma2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit WPWS5'-AMP-activated protein kinase subunit gamma-2

Research Areas for PRKAG2

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Lipid and Metabolism