PPP2R4 Products

Description

Protein phosphatase 2A is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2A holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B' family. This gene encodes a specific phosphotyrosyl phosphatase activator of the dimeric form of protein phosphatase 2A. Alternative splicing results in multiple transcript variants encoding different isoforms.

Bioinformatics

Entrez	110854 Mouse 362102 Rat 5524 Human
Uniprot	NM_178000 Human NP_066954 Human NP_066954.2 Human NP_821068.1 Human
Product By Gene ID	5524
Alternate Names	EC 5.2.1.8 MGC2184 Phosphotyrosyl phosphatase activator PP2A phosphatase activator PP2A subunit B' isoform PR53 PP2A PP2A, subunit B', PR53 isoform protein phosphatase 2A activator, regulatory subunit 4 regulatory subunit B' (PR 53) serine/threonine-protein phosphatase 2A activator Serine/threonine-protein phosphatase 2A regulatory subunit 4 Serine/threonine-protein phosphatase 2A regulatory subunit B'

Research Areas for PPP2R4

Find related products by research area and learn more about each of the different research areas below.

Protein Phosphatase