Species: Hu, Mu, Rt, Pm, Bv, Xp
Applications: WB, ICC/IF, IHC, IP, ChIP
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, KD
Host: Mouse Monoclonal
Species: Hu, Mu, Rt, Bv, Ca, Eq, Pm, RM, Pm, Pm
Applications: WB, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: WB, ELISA, MA, PAGE, AP
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Description
POU3F2 belongs to a large family of transcription factors that bind to the octameric DNA sequence ATGCAAAT. Most of these proteins share a highly homologous region, referred to as the POU domain, that occurs in several mammalian transcription factors, including the octamer-binding proteins Oct1 (POU2F1; MIM 164175) and Oct2 (POU2F2; MIM 164176) and the pituitary protein Pit1 (PIT1; MIM 173110). Class III POU genes are expressed predominantly in the central nervous system (CNS). It is likely that CNS-specific transcription factors such as these play an important role in mammalian neurogenesis by regulating their diverse patterns of gene expression (Schreiber et al., 1993 [PubMed 8441633]; Atanasoski et al., 1995 [PubMed 7601453]).[supplied by OMIM]
Bioinformatics
| Uniprot |
Human
Human
Human
|
| Product By Gene ID |
5454 |
| Alternate Names |
- Brain-2
- Brain-specific homeobox/POU domain protein 2
- brn-2
- Brn-2
- BRN2brain-2
- Nervous system-specific octamer-binding transcription factor N-Oct-3
- oct-7
- Oct-7
- OCT7POU domain class 3, transcription factor 2
- Octamer-binding protein 7
- Octamer-binding transcription factor 7
- OTF7
- OTF-7
- POU class 3 homeobox 2
- POU domain, class 3, transcription factor 2
- POUF3
|
