PKN2 Products

Description

Protein-kinase-C-related kinases (PRKs) (1) are part of the lipid-regulated protein kinases (PKC) which also include liver PAK & PKN (2-3). Human PRK1 and PRK2 share structurally similar catalytic domains, but less similar N-terminal regulatory regions suggesting different regulatory domain functions. PRK1 and PRK2, as well as a third member of this family, PRK3, show distinct patterns of expression in adult tissues. Additionally, the serine-threonine kinase PRK2 can be specifically cleaved by caspase-3 (and/or caspase-3-like subfamily members) during apoptosis (4).

Bioinformatics

Entrez	109333 Mouse 207122 Rat 5586 Human
Uniprot	NP_006247 Human Q16513 Human
Product By Gene ID	5586
Alternate Names	cardiolipin-activated protein kinase Pak2 EC 2.7.11 EC 2.7.11.13 PAK2 Pak-2 PRK2MGC150606 PRKCL2PRO2042 Protein kinase C-like 2MGC71074 protein kinase N2 Protein-kinase C-related kinase 2 serine/threonine-protein kinase N2

Research Areas for PKN2

Find related products by research area and learn more about each of the different research areas below.

Phospho-Specific
Protein Kinase