pan Cadherin Products

Description

Cadherins are members of a multigene family of single chain glycoprotein receptors mediating calcium dependent cell-cell adhesion. They play an important role in the growth and development of cells via the mechanisms of control of tissue architecture and the maintenance of tissue integrity. Cadherins are expressed in a tissue specific manner and and are required for assembly of cells into solid tissue. Individual cadherin molecules are known to co-operate with each other to form a linear cell adhesion zipper. In adhesion junctions cadherins are bound to beta and gamma catenins which in turn bind to alpha catenin, an actin binding protein. Cadherins play an important part in tumor invasion and metastasis. This product is useful for the detection of members of the cadherin family or genetically engineered proteins containing the C-terminal cadherin tail, and for demonstration of adherens type cell-cell junctions regardless of their cadherin type.

Bioinformatics

Uniprot	ENSP00000261769 Human NP_004351 Human P08641 Chicken P12830 Human
Product By Gene ID	999
Alternate Names	Arc-1 cadherin 1, E-cadherin (epithelial) cadherin 1, type 1, E-cadherin (epithelial) cadherin-1 calcium-dependent adhesion protein, epithelial CAM 120/80 CD324 antigen CD324 CDHE cell-CAM 120/80 ECAD E-cadherin Epithelial cadherin LCAM UVOE-Cadherin uvomorulin Uvomorulin

Research Areas for pan Cadherin

Find related products by research area and learn more about each of the different research areas below.

Cancer
Cell Cycle and Replication
Cellular Markers
Extracellular Matrix
Plasma Membrane Markers
Signal Transduction