Species: Hu, Mu, Rt, Ca, Pm
Applications: WB, Flow, ICC/IF, IHC
Host: Mouse Monoclonal
Species: Hu, Mu, Rt
Applications: WB
Host: Mouse Monoclonal
Species: Hu, Mu, Rt
Applications: WB, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: ELISA
Species: Hu
Applications: WB
Species: Hu
Applications: PAGE
Species: Hu
Applications: AC
Description
BCAR1/p130CAS functions as a scaffolding protein for components of various kinase signaling pathways. It is involved in integrin signaling for cell motility as well as netrin signaling for the guidance of commissural axons. Overexpression of BCAR1/p130CAS has been shown to confer antiestrogen resistance in breast cancer cells. Alternate names for BCAR1/p130CAS include breast cancer anti-estrogen resistance protein 1, CRK-associated substrate, CAS scaffolding protein family member 1, CAS, and CRKAS.
Bioinformatics
| Entrez |
Mouse
Rat
Human
|
| Uniprot |
Human
Human
Human
Human
|
| Product By Gene ID |
9564 |
| Alternate Names |
- breast cancer estrogen resistance 1
- Cas scaffolding protein family member 1
- CAS1
- CASFLJ45059
- CASS1CRKASbreast cancer estrogen resistance protein 1
- Crkas
- Crk-associated substrate p130Cas
- CRK-associated substrate
- FLJ12176
- P130Cas
- p130cas
|
Research Areas for p130Cas/BCAR1
Find related products by research area and learn more about each of the different research areas below.
Phospho-Specific
