OSTM1 Products

Description

OSTM1 encodes a protein that may be involved in the degradation of G proteins via the ubiquitin-dependent proteasome pathway. The encoded protein binds to members of subfamily A of the regulator of the G-protein signaling (RGS) family through an N-terminal leucine-rich region. This protein also has a central RING finger-like domain and E3 ubiquitin ligase activity. This protein is highly conserved from flies to humans. Defects in this gene may cause the autosomal recessive, infantile malignant form of osteopetrosis. [provided by RefSeq]

Bioinformatics

Uniprot	NM_014028 Human NP_054747.2 Human Q86WC4 Human
Product By Gene ID	28962
Alternate Names	GIPN GLGAIP-interacting protein N terminus grey-lethal osteopetrosis HSPC019 OPTB5 osteopetrosis associated transmembrane protein 1 osteopetrosis-associated transmembrane protein 1