Orc2 Products

Description

The origin recognition complex (ORC) is a highly conserved six subunits protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. This protein forms a core complex with ORC3L, -4L, and -5L. It also interacts with CDC45L and MCM10, which are proteins known to be important for the initiation of DNA replication. This protein has been demonstrated to specifically associate with the origin of replication of Epstein-Barr virus in human cells, and is thought to be required for DNA replication from viral origin of replication.

Bioinformatics

Uniprot	AAH14834 Human NM_006190 Human
Product By Gene ID	4999
Alternate Names	ORC2Lorigin recognition complex subunit 2 origin recognition complex protein 2 homolog origin recognition complex, subunit 2 (yeast homolog)-like origin recognition complex, subunit 2 homolog (yeast) origin recognition complex, subunit 2 homolog origin recognition complex, subunit 2 origin recognition complex, subunit 2-like (yeast) origin recognition complex, subunit 2-like

Research Areas for Orc2

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Cell Cycle and Replication