Neurokinin B Products

Description

The Neurokinins, also known as Tachykinins, belong to an evolutionary conserved family of peptide neurotransmitters that share a c-terminal sequence and have an established role in neurotransmission. The mammalian tachykinins include substance P (NK1), neurokinin A (NKA) and neurokinin B (NKB) which exert their effects by binding to specific receptors. Tachykinin peptides are important in the mediation of many physiological and pathological processes including inflammation, pain, migraine headache and allergy induced asthma.

Three tachykinin receptor types have been characterized, NK-1, NK-2 and NK-3 which have preferential affinities for SP, NKA and NKB respectively. All three receptors share a high degree of sequence homology, have seven transmembrane spanning domains and similar signal transduction mechanisms (e.g. G-protein coupled activation of phospholipase C).

Bioinformatics

Uniprot	AAH32145 Human NM_013251 Human NP_037383 Human P55099 Mouse
Product By Gene ID	6866
Alternate Names	gamma tachykinin 3 neurokinin beta neurokinin B-like neuromedin K preprotachykinin B PRO1155 tachykinin 3 tachykinin-3 ZNEUROK1NKNBNKB

Research Areas for Neurokinin B

Find related products by research area and learn more about each of the different research areas below.

GPCR
Neuroscience
Neurotransmission