Species: Hu, Mu, Rt
Applications: WB, Simple Western, ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt, Ca, Fe
Applications: WB, ICC/IF, IHC, KO
Host: Rabbit Polyclonal
Species: Hu
Applications: WB, ELISA, ICC/IF, IHC
Host: Mouse Monoclonal
Species: Hu
Applications: WB
Species: Hu
Applications: WB, ELISA, MA, PAGE, AP
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Description
MVP encodes the major vault protein which is a lung resistance-related protein. Vaults are multi-subunit structures that may be involved in nucleo-cytoplasmic transport. This protein mediates drug resistance, perhaps via a transport process. It is widely distributed in normal tissues, and overexpressed in multidrug-resistant cancer cells. The protein overexpression is a potentially useful marker of clinical drug resistance. This gene produces two transcripts by using two alternative exon 2 sequences; however, the open reading frames are the same in both transcripts.
Bioinformatics
| Uniprot |
Human
Human
Human
Human
|
| Product By Gene ID |
9961 |
| Alternate Names |
- LRPVAULT1
- Lung resistance-related protein
- major vault protein
|
Research Areas for MVP
Find related products by research area and learn more about each of the different research areas below.
Cancer
