Species: Hu, Mu, Rt, Po, Bv
Applications: WB, IHC
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt
Applications: IHC
Host: Rabbit Polyclonal
Species: Hu, Ce
Applications: WB, ELISA, IP
Host: Mouse Monoclonal
Species: Hu
Applications: WB
Species: Hu
Applications: PAGE
Species: Hu
Applications: AC
Description
MAT1A and MAT2A are catalytic subunits of methionine adenosyltransferase (MAT), which catalyzes the formation of S-adenosyltransferase for methionine catabolism. Inactivation of MAT1A has been linked to liver disease. In addition, in certain liver cancers, expression of MAT1A is replaced by expression of MAT1B. Overexpression of MAT2A has also been observed in colon cancer, leading to the proposal that MAT2A facilitates cancer cell growth.
MAT1A and MAT2A antibodies are useful tools for cancer research and liver function research.
Bioinformatics
Entrez |
Human |
Uniprot |
Human Human Human Human |
Product By Gene ID |
4143 |
Alternate Names |
- AdoMet synthase 1
- adoMet synthetase 1
- AMS1
- MAT
- MATA1MAT 1
- MAT-I/III
- Methionine adenosyltransferase 1
- methionine adenosyltransferase I, alpha
- Methionine adenosyltransferase I/III
- S-adenosylmethionine synthase isoform type-1
- S-adenosylmethionine synthetase isoform type-1
- SAMS
- SAMS1EC 2.5.1.6
|
Research Areas for MAT1A
Find related products by research area and learn more about each of the different research areas below.
Lipid and Metabolism