LEF1 Products

Description

Lymphoid enhancer-binding factor-1 (LEF1) is a 48-kD nuclear protein that is expressed in pre-B and T cells. It binds to a functionally important site in the T-cell receptor-alpha (TCRA; MIM 186880) enhancer and confers maximal enhancer activity. LEF1 belongs to a family of regulatory proteins that share homology with high mobility group protein-1 (HMG1; MIM 163905).[supplied by OMIM]

Bioinformatics

Entrez	161452 Rat 16842 Mouse 51176 Human
Uniprot	AAH50632 Human NM_016269 Human NP_057353 Human NP_057353.1 Human Q9UJU2 Human
Product By Gene ID	51176
Alternate Names	DKFZp586H0919 FLJ46390 LEF-1 lymphoid enhancer-binding factor 1 T cell-specific transcription factor 1-alpha TCF1ALPHA TCF1-alpha

Research Areas for LEF1

Find related products by research area and learn more about each of the different research areas below.

DNA Repair
DNA replication, Transcription, Translation and Splicing
Signal Transduction
Transcription Factors and Regulators
Wnt Signaling Pathway

Related LEF1 Blog Posts

Check out the latest blog posts on LEF1.

Beta Catenin in Cell Adhesion and T-cell Signaling Beta Catenin is a cytosolic, 88 kDa intracellular protein that tightly associates with cell surface cadherin glycoproteins. It is one member of the catenin family that includes alpha Catenin, beta Catenin, and gamma Catenin. Colocalization studies usi...    Read more.

The role of Wnts in neuroinflammation By Michalina Hanzel, PhDThe multifaceted roles of the Wnt family of glycoproteins have been extensively characterized throughout embryonic development and adult homeostasis. The highly conserved, cell- and tissue- s...    Read more.

Read more LEF1 related blogs.