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KLRC4 Products

Antibodies
KLRC4 Antibody - Azide and BS ...
KLRC4 Antibody - Azide and BSA Free
NBP3-04739
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC
Host: Rabbit Polyclonal
Formulation Catalog # Availability Price  
KLRC4 Antibody (1D10)
KLRC4 Antibody (1D10)
H00008302-M03
Species: Hu
Applications: WB, ELISA
Host: Mouse Monoclonal
KLRC4 Antibody
KLRC4 Antibody
NBP1-31161
Species: Hu, Pm
Applications: WB
Host: Rabbit Polyclonal
Lysates
KLRC4 Overexpression Lysate
KLRC4 Overexpression Lysate
NBL1-12364
Species: Hu
Applications: WB
Proteins
Recombinant Human KLRC4 GST ( ...
Recombinant Human KLRC4 GST (N-Ter...
H00008302-P01
Species: Hu
Applications: WB, ELISA, MA, AP

Description

Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. KLRC4 is a member of the NKG2 group which are expressed primarily in natural killer (NK) cells and encodes a family of transmembrane proteins characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C-type lectin domain. The NKG2 gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed on NK cells. The 3' end of the KLRC4 transcript includes the first non-coding exon found at the 5' end of the adjacent D12S2489E gene transcript. [provided by RefSeq]

Bioinformatics

Entrez Human
Uniprot Human
Human
Product By Gene ID 8302
Alternate Names
  • D12S2489E
  • FLJ17759
  • killer cell lectin-like receptor subfamily C, member 4
  • natual killer cell group 2-F
  • NK cell receptor F
  • NKG2-F type II integral membrane protein
  • NKG2-F
  • NKG2-F-activating NK receptor
  • NKG2FFLJ78582

Related KLRC4 Blog Posts

Check out the latest blog posts on KLRC4.
Harnessing Natural Killer Cell Activity for Anti-Tumor Immunotherapy
By Victoria Osinski, PhDWhat’s “Natural” About Natural Killer (NK) Cells?For immunologists, the term cytotoxicity often conjures up images of an army of antigen specific CD8+ T cells deploying to ...    Read more.
Read more KLRC4 related blogs.