Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB, ELISA
Host: Mouse Monoclonal
Species: Hu, Pm
Applications: WB
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: WB, ELISA, MA, AP
Description
Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. KLRC4 is a member of the NKG2 group which are expressed primarily in natural killer (NK) cells and encodes a family of transmembrane proteins characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C-type lectin domain. The NKG2 gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed on NK cells. The 3' end of the KLRC4 transcript includes the first non-coding exon found at the 5' end of the adjacent D12S2489E gene transcript. [provided by RefSeq]
Bioinformatics
Entrez |
Human |
Uniprot |
Human Human |
Product By Gene ID |
8302 |
Alternate Names |
- D12S2489E
- FLJ17759
- killer cell lectin-like receptor subfamily C, member 4
- natual killer cell group 2-F
- NK cell receptor F
- NKG2-F type II integral membrane protein
- NKG2-F
- NKG2-F-activating NK receptor
- NKG2FFLJ78582
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