Kinesin 5A Products

Description

Kinesin 5A is part of a superfamily of microtubule-associated motor proteins involved in a variety of cellular processes including membranous organelle transport and cell division. Kinesin has been found in a variety of organisms and cell types and is subject to spatial and temporal regulation. These proteins have a modular structure including a conserved motor domain of approximately 350 amino acids, which is responsible for microtubule binding and ATP hydrolysis. In addition to the motor domain, subfamily members share common domain organization, exhibit sequence similarity, motility properties, and cellular functions outside of the motor domain. There are currently three known Kinesin 5 family members denoted as A, B, and C. Kinesin 5A and kinesin 5C appear to be exclusively neuronal, whereas kinesin 5B appears to be ubiquitous in its expression.

Bioinformatics

Entrez	16572 Mouse 3798 Human
Uniprot	NP_004975 Human NP_004975. Human Q12840 Human
Product By Gene ID	3798
Alternate Names	D12S1889 KIF5A variant protein kinesin family member 5A kinesin heavy chain isoform 5A Kinesin heavy chain neuron-specific 1 kinesin, heavy chain, neuron-specific MY050 Neuronal kinesin heavy chain NKHC1 NKHCspastic paraplegia 10 (autosomal dominant) SPG10

Research Areas for Kinesin 5A

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Cytoskeleton Markers