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Kinesin 5A Antibody [FITC]

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Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ELISA, ICC/IF, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
FITC

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Kinesin 5A Antibody [FITC] Summary

Immunogen
Antibody was raised against a 20 amino acid synthetic peptide from near the carboxy terminus of human KIF5. The immunogen is located within amino acids 880 - 930 of KIF5. Amino Acid Squence: KDKRRYQQEVDRIKEAVRYK
Specificity
At least three isoforms of KIF5 are known to exist; this antibody will recognize all three isoforms.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
KIF5A
Purity
Peptide affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

0

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Peptide affinity purified

Alternate Names for Kinesin 5A Antibody [FITC]

  • D12S1889
  • KIF5A variant protein
  • kinesin family member 5A
  • kinesin heavy chain isoform 5A
  • Kinesin heavy chain neuron-specific 1
  • kinesin, heavy chain, neuron-specific
  • MY050
  • Neuronal kinesin heavy chain
  • NKHC1
  • NKHCspastic paraplegia 10 (autosomal dominant)
  • SPG10

Background

Kinesin 5A is part of a superfamily of microtubule-associated motor proteins involved in a variety of cellular processes including membranous organelle transport and cell division. Kinesin has been found in a variety of organisms and cell types and is subject to spatial and temporal regulation. These proteins have a modular structure including a conserved motor domain of approximately 350 amino acids, which is responsible for microtubule binding and ATP hydrolysis. In addition to the motor domain, subfamily members share common domain organization, exhibit sequence similarity, motility properties, and cellular functions outside of the motor domain. There are currently three known Kinesin 5 family members denoted as A, B, and C. Kinesin 5A and kinesin 5C appear to be exclusively neuronal, whereas kinesin 5B appears to be ubiquitous in its expression.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for Kinesin 5A Antibody (NBP1-76816F) (0)

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol KIF5A