KCNH1 Products

Description

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit of a voltage-gated non-inactivating delayed rectifier potassium channel. It is activated at the onset of myoblast differentiation. The gene is highly expressed in brain and in myoblasts. Overexpression of the gene may confer a growth advantage to cancer cells and favor tumor cell proliferation. Alternative splicing of this gene results in two transcript variants encoding distinct isoforms.

Bioinformatics

Entrez	16510 Mouse 3756 Human 65198 Rat
Uniprot	NP_002229 Human NP_758872 Human Q63472 Rat
Product By Gene ID	3756
Alternate Names	EAG channel 1 EAG1 EAGeag1 Ether-a-go-go potassium channel 1 ether-a-go-go, Drosophila, homolog of hEAG1 h-eageag Kv10.1 MGC142269 potassium channel, voltage-gated, subfamily H, member 1 potassium voltage-gated channel subfamily H member 1 potassium voltage-gated channel, subfamily H (eag-related), member 1 Voltage-gated potassium channel subunit Kv10.1