Integrin alpha 2b/CD41 Products

Description

Integrin alpha 2b (CD41) is a calcium-dependent, noncovalently associated heterodimer and contains a heavy chain (GPIIb alpha) and a light chain (GPIIb beta) linked by a single disulfide bond. The Integrin alpha 2B chain interacts with the Integrin beta 3 subunit/CD61 to form the platelet glycoprotein complex, gpIIb/IIIa. It is expressed on platelets and megakaryocytes. Ligands for the gpIIb/IIIa heterodimer include fibrinogen, von Willebrand factor, fibronectin, vitronectin, and thrombospondin. The gpIIb/IIIa complex is the major Integrin on platelets and is important for platelet adhesion and aggregation.

Bioinformatics

Entrez	16399 Mouse 29350 Rat 3674 Human
Uniprot	NP_000410 Human P08514 Human
Product By Gene ID	3674
Alternate Names	CD41 antigen CD41 CD41BHPA3 GP2Bintegrin alpha-IIb GPalpha IIb GPIIb GTA integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigenCD41) integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigenCD41B) ITGAB platelet fibrinogen receptor, alpha subunit Platelet membrane glycoprotein IIb platelet-specific antigen BAK

Research Areas for Integrin alpha 2b/CD41

Find related products by research area and learn more about each of the different research areas below.

Angiogenesis
Cancer
Cell Biology
Cellular Markers
Cytoskeleton Markers
Extracellular Matrix
Immunology
Signal Transduction
Stem Cell Markers