Species: Hu, Mu, Rt
Applications: WB, Simple Western, ICC/IF
Host: Rabbit Polyclonal
Species: Hu
Applications: WB, ELISA
Host: Mouse Monoclonal
Species: Hu
Applications: WB, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: WB
Species: Hu
Applications: Enzyme Activity
Description
IMPDH1 is encoded by this gene acts as a homotetramer to regulate cell growth. The encoded protein is an enzyme that catalyzes the synthesis of xanthine monophosphate (XMP) from inosine-5'-monophosphate (IMP). This is the rate-limiting step in the de novo synthesis of guanine nucleotides. Defects in this gene are a cause of retinitis pigmentosa type 10 (RP10). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
Bioinformatics
| Entrez |
Human
|
| Uniprot |
Human
Human
Human
Human
Human
Human
|
| Product By Gene ID |
3614 |
| Alternate Names |
- DKFZp781N0678
- EC 1.1.1.205
- IMP (inosine 5'-monophosphate) dehydrogenase 1
- IMP (inosine monophosphate) dehydrogenase 1
- IMP dehydrogenase 1
- IMPD 1
- IMPD
- IMPD1
- IMPDH 1
- IMPDH-I
- inosine-5'-monophosphate dehydrogenase 1
- LCA11RP10
- retinitis pigmentosa 10 (autosomal dominant)
- sWSS2608
|
![Western Blot IMPDH1 Antibody [Unconjugated]](http://images.novusbio.com/fullsize2/IMP_Dehydrogenase_1_AF8554_Western_Blot_16658.jpg)
![Immunocytochemistry IMPDH1 Antibody [Unconjugated]](http://images.novusbio.com/fullsize2/IMP_Dehydrogenase_1_AF8554_Immunocytochemistry__Immunofluorescence_17605.jpg)
![Immunocytochemistry IMPDH1 Antibody [Unconjugated]](http://images.novusbio.com/fullsize2/af8554_human-mouse-rat-imp-dehydrogenase-1-impdh1-aff-pur-pab-immunocytochemistry-842022162057.jpg)
![Simple Western IMPDH1 Antibody [Unconjugated]](http://images.novusbio.com/fullsize2/af8554_human-mouse-rat-imp-dehydrogenase-1-impdh1-aff-pur-pab-simple-western-1342022153711.jpg)
