Species: Hu
Applications: WB, IP
Host: Mouse Monoclonal
Species: Hu, Mu, Rt, Bv, Ca, Pm
Applications: WB, Simple Western, ICC/IF
Host: Rabbit Polyclonal
Species: Hu
Applications: IHC
Host: Mouse Monoclonal
Species: Hu
Applications: ELISA
Species: Hu
Applications: WB
Species: Hu
Applications: Enzyme Activity
Species: Hu
Applications: AC
Description
htrA1 encodes a member of the trypsin family of serine proteases. This protein is a secreted enzyme that is proposed to regulate the availability of insulin-like growth factors (IGFs) by cleaving IGF-binding proteins. It has also been suggested to be a regulator of cell growth. Variations in the promoter region of this gene are the cause of susceptibility to age-related macular degeneration type 7. [provided by RefSeq]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Bioinformatics
| Entrez |
Human
|
| Uniprot |
Human
Human
|
| Product By Gene ID |
5654 |
| Alternate Names |
- ARMD7
- EC 3.4.21
- EC 3.4.21.108
- High-temperature requirement A serine peptidase 1
- HtrA serine peptidase 1
- L56
- ORF480
- Serine protease 11
- serine, 11 (IGF binding)
|
![Western Blot HTRA1/PRSS11 Antibody (275615) [Unconjugated]](http://images.novusbio.com/fullsize2/HTRA1_MAB2916_Western_Blot_11032.jpg)
![Western Blot HTRA1/PRSS11 Antibody (275615) [Unconjugated]](http://images.novusbio.com/fullsize/mab2916_human-htra1-prss11-mab-clone-275615-41202412514842.jpg)
![Western Blot HTRA1/PRSS11 Antibody (275615) [Unconjugated]](http://images.novusbio.com/fullsize/mab2916_human-htra1-prss11-mab-clone-275615-41202412513811.jpg)
![Immunohistochemistry HTRA1/PRSS11 Antibody (275603) [Unconjugated]](http://images.novusbio.com/fullsize2/HTRA1_MAB29161_Immunohistochemistry_23446.jpg)
