Species: Hu
Applications: ICC/IF
Host: Mouse Monoclonal
Species: Hu, Mu, Rt
Applications: IHC
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt
Applications: WB, ICC/IF
Host: Rabbit Polyclonal
Species: Hu
Applications: ELISA
Species: Hu
Applications: ELISA
Species: Hu
Applications: WB
Species: Hu
Applications: WB, ELISA, MA, PAGE, AP
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Description
The GRIA3 gene encodes for glutamate receptor 3 with an isoform flop and flip of 894 amino acids, 101 kDA each. Glutamate receptors function as a ligand-gated ion channel in the central nervous system and are the predominant excitatory neurotransmitter receptors in the brain. GRIA3 is involved in glutamic acid signaling, calcium channels, CREB pathways, pathogenesis of ALS, and glutamatergic synapses. It is known to interact with GRIA2, DLG4, NSF, SQSTM1, and SDCBP. GRIA3 has been researched with various diseases such as bipolar disorder, encephalitis, mood disorder, rett syndrome, lateral sclerosis, auditory neuropathy, epilepsy, smith-fineman-myers syndrome, and nonsyndromic deafness, and canavan disease.
Bioinformatics
Entrez |
Human Rat Mouse |
Uniprot |
Human Human Human Human |
Product By Gene ID |
2892 |
Alternate Names |
- AMPA 3
- AMPA-selective glutamate receptor 3
- GluA3
- GluR-3
- GluR-C
- GLUR-C
- GluR-K3
- GLUR-K3
- glutamate receptor C
- glutamate receptor subunit 3
- glutamate receptor, ionotrophic, AMPA 3
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