Species: Hu, Mu
Applications: WB, ChIP, ICC/IF
Host: Goat Polyclonal
Species: Hu, Mu
Applications: WB, Flow, ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt, Ch, Pm
Applications: WB, ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB, ELISA, MA, PAGE, AP
Species: Hu
Applications: AC
Description
Gli-3 (also known as Zinc Finger Protein Gli-3 or GLI-Kruppel family member GLI-3) belongs to the GLI C2H2-type zinc-finger protein family and contains 5 C2H2-type zinc fingers. Gli-3 is very important for normal limb and brain development and is implicated in the transduction of Shh signal. Gli-3 is a nuclear protein expressed in a wide variety of normal adult tissues, including lung, colon, spleen, placenta, testis, and myometrium. Defects in Gli-3 are the cause of Greig cephalo-polysyndactyly syndrome (GCPS); an autosomal dominant disorder-affecting limb and craniofacial development. Two isoforms of human Gli-3 have been reported. One is the fulllength protein at ~170-190kDa and the other is a truncated isoform at ~80kDa.
Bioinformatics
| Entrez |
Rat
Mouse
Human
|
| Uniprot |
Human
Human
Human
|
| Product By Gene ID |
2737 |
| Alternate Names |
- ACLSPAPAPHS
- GCPS
- GLI family zinc finger 3
- GLI3 form of 190 kDa
- GLI3 full length protein
- GLI3-190
- GLI3FL
- GLI-Kruppel family member GLI3
- glioma-associated oncogene family zinc finger 3
- Greig cephalopolysyndactyly syndrome
- oncogene GLI3
- PAP-A
- PAPA1
- PAPBDNA-binding protein
- PPDIV
- zinc finger protein GLI3
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