Species: Hu
Applications: WB
Host: Goat Polyclonal
Species: Hu, Mu
Applications: WB, ELISA, Func, IP
Host: Mouse Monoclonal
Species: Hu
Applications: WB, ELISA, Flow, CyTOF-ready
Host: Mouse Monoclonal
Species: Hu
Applications: WB
Species: Hu
Applications: Binding Activity
Species: Hu
Applications: Bioactivity
Species: Mu
Applications: Bioactivity
Description
FZD5 is a Frizzled Receptor that mediates Wnt signaling. FZD5 is associated with limb bud and bone marrow stem cell development. FZD5 contributes to the activated state of fibroblast-like synoviocytes from patients with rheumatoid arthritis. Recently, FZD5 has been implicated in melanoma metastasis through the Wnt5a and PKC pathway. FZD5 has been reported to be expressed in fetal kidney, fetal and adult liver, fetal lung, and adult pancreas. ESTs have been isolated from bone, liver/spleen, placenta, and prostate libraries. FZD5 was cloned from a retina cDNA library.
Bioinformatics
| Entrez |
Mouse
Rat
Human
|
| Uniprot |
Human
Human
Human
|
| Product By Gene ID |
7855 |
| Alternate Names |
- C2orf31
- chromosome 2 open reading frame 31
- DKFZp434E2135
- DKFZP434E2135
- frizzled (Drosophila) homolog 5
- frizzled homolog 5 (Drosophila)
- frizzled-5
- fz-5
- Fz-5
- fzE5
- FzE5
- HFZ5
- hFz5
- MGC129692
- seven-transmembrane receptor frizzled-5
- Wnt receptor
|
![Bioactivity Frizzled-5 [Unconjugated]](http://images.novusbio.com/fullsize2/Frizzled5_9060FZ_1096.jpg)