FoxP2 Products

Description

FOXP2 encodes an evolutionarily conserved transcription factor expressed in fetal and adult brain. This transcription factor is a member of the forkhead/winged-helix (FOX) family of transcription factors, and contains a FOX DNA-binding domain and a large polyglutamine tract. Members of the FOX family of transcription factors are regulators of embryogenesis. The product of this gene is thought to be required for proper development of speech and language regions of the brain during embryogenesis. Although a point mutation in this gene has been associated with the KE pedigree segregating developmental verbal dyspraxia, no association between mutations in this gene and another speech disorder, autism, has been found. Four alternative transcripts encoding three different isoforms have been identified.

Bioinformatics

Entrez	114142 Mouse 500037 Rat 93986 Human
Uniprot	NP_055306 Human NP_055306.1 Human NP_683697 Human
Product By Gene ID	93986
Alternate Names	CAG repeat protein 44 CAGH44TNRC10forkhead box protein P2 DKFZp686H1726 forkhead box P2 forkhead/winged-helix transcription factor SPCH1 trinucleotide repeat containing 10 Trinucleotide repeat-containing gene 10 protein